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Ventricular Arrhythmias: Medical Therapy, Device Treatment, and Indications for Electrophysiologic Study

  • Philip T. Sager
    Correspondence
    Corresponding Author: Section of Cardiology, 3 FMP, Yale University School of Medicine, 333 Cedar Street, P.O. Box 3333, New Haven, CT 06510
    Affiliations
    Senior Postdoctoral Fellow, Section of Cardiology, Yale University School of Medicine, New Haven, Connecticut
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  • William P. Batsford
    Affiliations
    Associate Professor of Medicine, Yale University School of Medicine; and Director of Clinical Electrophysiology Laboratory, Yale-New Haven Hospital, New Haven, Connecticut
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      This paper is only available as a PDF. To read, Please Download here.
      Sustained ventricular arrhythmias commonly occur in post-myocardial infarction patients. Electrophysiology studies have greatly contributed to understanding the mechanisms of these arrhythmias and in guiding therapy. In addition to pharmacologic therapy, new treatment modalities-which include arrhythmia surgery, device therapy, and percutaneous catheter ablation-have resulted in a significantly improved outcome in patients with malignant ventricular arrhythmias
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      References

        • Anderson J.L.
        • Mason J.W.
        Testing the efficacy of antiarrhythmic drugs.
        N Engl J Med. 1986; 313: 391
        • Au P.K.
        • Bhandari A.K.
        • Bream R.
        • et al.
        Proarrhythmic effects of antiarrhythmic drugs during programmed ventricular stimulation in patients without ventricular tachycardia.
        Am J Cardiol. 1987; 9: 389
        • Bastian B.C.
        • Macfarlane P.W.
        • McLaughlin J.H.
        • et al.
        A aprospective randomized trial of tocainide in patients following myocardial infarction.
        Am Heart J. 1980; 100: 1017
        • Beihassen B.
        • Miller H.I.
        • Laniado S.
        Catheter ablation of incessant ventricular tachycardia refractory to external cardioversions.
        Am J Cardiol. 1985; 55: 1637
        • Bhandari A.K.
        • Rose J.S.
        • Kotlewski A.
        • et al.
        Frequency and significance of induced sustained ventricular tachycardia or fibrillation two weeks after acute myocardial infarction.
        Am J Cardiol. 1985; 56: 737
        • Bigger J.T.
        • Fleiss J.L.
        • Kleiger R.
        • et al.
        The relationship among ventricular arrhythmias, left ventricular dysfunction, and mortality in the 2 years after myocardial infarction.
        Circulation. 1984; 69: 250
        • Bigger J.T.
        • Heller C.A.
        • Wenger T.L.
        • et al.
        Risk stratification after acute myocardial infarction.
        Am J Cardiol. 1978; 42: 202
        • Bigger J.T.
        • Weld F.M.
        • Rolnitzky L.M.
        Prevalence, characteristics and significance of ventricular tachycardia (three or more complexes) detected with ambulatory electrocardiographic recording in the late hospital phase of acute myocardial infarction.
        Am J Cardiol. 1981; 48: 815
        • Braat S.H.
        • de Zwann C.
        • Brugada P.
        • et al.
        Value of left ventricular ejection fraction in extensive anterior infarction to predict development of ventricular tachycardia.
        Am J Cardiol. 1983; 52: 686
        • Buxton A.E.
        • Marchlinski F.E.
        • Flores B.T.
        • et al.
        Non-sustained ventricular tachycardia in patients with coronary artery disease: Role of electrophysiology study.
        Circulation. 1987; 75: 1178
        • Chamberlin D.A.
        • Julian D.G.
        • Boyle D.M.
        • et al.
        Oral mexiletine in high-risk patients after myocardial infarction.
        Lancet. 1980; 2: 1324
        • Chau W.
        • Roth H.
        • Summers C.
        • et al.
        Programmed stimulation versus ambulatory monitoring for therapy of malignant arrhythmias.
        Circulation. 1983; 68: 111-155
        • Cobb L.A.
        • Werner J.A.
        • Trobaugh G.B.
        Sudden cardiac death, I. A decade’s experience with out-of-hospital resuscitation.
        Mod Concepts Cardiovasc Dis. 1980; 19: 31
        • Conley M.J.
        • McNeer J.F.
        • Lee K.L.
        • et al.
        Cardiac arrest complicating acute myocardial infarction: Predictability and prognosis.
        Am J Cardiol. 1977; 39: 7
        • Davis H.T.
        • DeCamilla J.
        • Bayer L.W.
        • et al.
        Survivorship patterns in the posthospital phase of myocardial infarction.
        Circulation. 1979; 60: 1252
        • Denniss A.R.
        • Baaijens D.
        • Cody D.V.
        • et al.
        Value of programmed stimulation and exercise testing in predicting one-year mortality after acute myocardial infarction.
        Am J Cardiol. 1985; 56: 213
        • Denniss A.R.
        • Richards D.A.
        • Cody D.V.
        • et al.
        Prognostic significance of ventricular tachycardia and fibrillation induced at programmed stimulation and delayed potentials detected on the signal-averaged electrocardiograms of survivors of acute myocardial infarction.
        Circulation. 1986; 74: 731
        • DeSilva R.A.
        • Hennekens C.H.
        • Lown B.
        • et al.
        Lignocaine prophylaxis in acute myocardial infarction: An evaluation of randomized trials.
        Lancet. 1981; 2: 855
        • DiMarco J.P.
        • Garan H.
        • Harthorne W.
        • et al.
        Intracardiac electrophysiologic techniques in recurrent syncope of unknown cause.
        Ann Intern Med. 1981; 95: 542
        • DiMarco J.P.
        • Lerman B.B.
        • Kron I.L.
        • et al.
        Sustained ventricular tachyarrhythmias within 2 months of acute myocardial infarction: Results of medical and surgical therapy in patients resuscitated from the initial episode.
        J Am Coll Cardiol. 1985; 6: 759
        • Dweyer E.M.
        • Greenberg H.
        • Case R.B.
        • et al.
        Association between transient pulmonary congestion during acute myocardial infarction and high incidence of death in six months.
        Am J Cardiol. 1986; 58: 900
        • Echt D.S.
        • Armstrong K.
        • Schmidt P.
        • et al.
        Clinical experience, complications, and survival in 70 patients with the automatic implantable cardioverter/defibrillator.
        Circulation. 1985; 71: 289
        • El-Sherif N.
        • Meyerburg R.J.
        • Scherlag B.J.
        • et al.
        Electrocardiographic antecedents of primary ventricular fibrillation: Value of the R-on-T phenomenon in myocardial infarction.
        Br Heart J. 1976; 38: 415
        • Epstein S.E.
        • Palmeri S.T.
        • Patterson R.E.
        Evaluation of patients after myocardial infarction: Indications for cardiac catheterization and surgical intervention.
        N Engl J Med. 1982; 307: 1487
        • Fisher J.D.
        • Kim S.G.
        • Furman S.
        • et al.
        Role of implantable pacemakers in control of recurrent ventricular tachycardia.
        Am J Cardiol. 1982; 49: 194
        • Garan H.
        • Fallon J.T.
        • Ruskin J.N.
        Sustained ventricular tachycardia in recent canine model myocardial infarction.
        Circulation. 1980; 62: 980
        • Garan H.
        • Ruskin J.N.
        • DiMarco J.P.
        • et al.
        Electrophysiologic studies before and after myocardial revascularization in patients with life-threatening ventricular arrhythmias.
        Am J Cardiol. 1983; 151: 519
        • Garan H.
        • Ruskin J.N.
        • DiMarco J.P.
        • et al.
        Refractory ventricular tachycardia complicating recovery from acute myocardial infarction: Treatment with map-guided infarctectomy.
        Am Heart J. 1984; 107: 571
        • Gianelly R.
        • von der Groeben J.O.
        • Spivak A.P.
        • et al.
        Effect of lidocaine on ventricular arrhythmias in patients with coronary heart disease.
        N Engl J Med. 1967; 277: 1215
        • Gillum R.F.
        • Folsom A.
        • Leupker R.V.
        • et al.
        Sudden death and acute myocardial infarction in a metropolitan area, 1970-1980: The Minnesota Heart Survey.
        N Engl J Med. 1983; 309: 1353
        • Gottlieb S.H.
        • Achuff S.C.
        • Melleits E.D.
        • et al.
        Prophylactic therapy of high-risk survivors of myocardial infarction: Lower mortality at 1 month but not at 1 year.
        Circulation. 1987; 74: 792
        • Hamer A.
        • Vohra J.
        • Hunt D.
        • et al.
        Prediction of sudden death by electrophysiologic studies in high risk patients surviving acute myocardial infarction.
        Am J Cardiol. 1982; 50: 223
        • Harken A.H.
        • Horowitz L.N.
        • Josephson M.E.
        Comparison of standard aneurysmectomy and aneurysmec-tomy with directed endocardial resection for the treatment of recurrent sustained ventricular tachycardia.
        J Thorac Cardiovasc Surg. 1980; 80: 527
        • Henning H.
        • Gilpin E.A.
        • Covell J.W.
        • et al.
        Prognosis after acute myocardial infarction: A multivariate analysis of mortality and survival.
        Circulation. 1979; 59: 1124
        • Hoffman B.F.
        • Rosen M.R.
        Cellular mechanisms for cardiac arrhythmias.
        Circ Res. 1981; 49: 1
        • Horowitz L.N.
        • Greenspan A.M.
        • Spielman S.R.
        • et al.
        Usefulness of electrophysiologic testing in evaluation of amiodarone therapy for sustained ventricular tachyarrhythmias associated with coronary artery disease.
        Am J Cardiol. 1984; 55: 367
        • Horowitz L.N.
        • Harken A.H.
        • Josephson M.E.
        • et al.
        Surgical treatment of ventricular arrhythmias in coronary artery disease.
        Ann Intern Med. 1981; 95: 88
        • Horowitz L.N.
        • Josephson M.E.
        • Farshidi A.
        • et al.
        Re-current sustained ventricular tachycardia, 3. Role of electrophysiologic study in selection of antiarrhythmic regimens.
        Circulation. 1978; 58: 986
        • Josephson M.E.
        • Harken A.H.
        • Horowitz L.N.
        Endocardial excision: A new surgical technique for the treatment of recurrent ventricular tachycardia.
        Circulation. 1979; 60: 1430
        • Josephson M.E.
        • Horowitz L.N.
        • Spielman S.R.
        • et al.
        Role of catheter mapping in the preoperative evaluation of ventricular tachycardia.
        Am J Cardiol. 1982; 49: 207
        • Kannel W.B.
        • Sorlie P.
        • McNamara P.M.
        Prognosis after initial myocardial infarction: The Framingham Study.
        Am J Cardiol. 1979; 44: 53
        • Kanovsky M.S.
        • Falcone R.
        • Dresden C.A.
        • et al.
        Identification of patients with ventricular tachycardia after myocardial infarction: Signal-averaged electrocardiogram, Holter monitoring, and cardiac catheterization.
        Circulation. 1984; 70: 264
        • Kennedy E.E.
        • Rosenfeld L.E.
        • McPherson C.A.
        • et al.
        Evaluation by serial electrophysiologic studies of an abbreviated oral loading regimen of amiodarone.
        Am J Cardiol. 1985; 56: 867
        • Kersschot I.E.
        • Brugada P.
        • Ramentol M.
        • et al.
        Effects of early reperfusion in acute myocardial infarction on arrhythmias induced by programmed stimulation: A prospective randomized study.
        J Am Coll Cardiol. 1986; 7: 1234
        • Koster R.W.
        • Dunning A.J.
        Intramuscular lidocaine for the prevention of lethal arrhythmias in the prehos-pitalization phase of acute myocardial infarction.
        N Engl J Med. 1985; 313: 1105
        • Krafchek J.
        • Lawrie G.M.
        • Roberts R.
        • et al.
        Surgical ablation of ventricular tachycardia: Improved results with a map-directed regional approach.
        Circulation. 1876; 73: 1239
        • Kuchar D.L.
        • Thorburn C.W.
        • Sammel N.L.
        Prediction of serious arrhythmic events after myocardial infarction: Signal averaged electrocardiogram, Holter monitoring and radionuclide ventriculography.
        J Am Coll Cardiol. 1987; 9: 531
        • Lie K.I.
        • Liem K.L.
        • Schuilenburg
        • et al.
        Early identification of patients developing late in-hospital ventricular fibrillation after discharge from the coronary care unit: A 5.5 year retrospective and prospective study of 1,897 patients.
        Am J Cardiol. 1978; 41: 674
        • Lie K.I.
        • Wellens H.J.
        • Durrer D.
        Characteristics and predictability of primary ventricular fibrillation.
        Eur J Cardiol. 1974; 1: 379
        • Lie K.I.
        • Wellens H.J.
        • van Capelle F.J.
        • et al.
        Lidocaine in the prevention of primary ventricular fibrillation: A double-blind, randomized study of 212 consecutive patients.
        N Engl J Med. 1974; 291: 1324
        • Luria M.H.
        • Debanne S.M.
        • Osman M.I.
        Long-term follow-up after recovery from acute myocardial infarction.
        Arch Intern Med. 1985; 145: 1592
        • Marchlinski F.E.
        • Buxton A.E.
        • Waxman H.L.
        • et al.
        Identifying patients at risk of sudden death after myocardial infarction: Value of response to programmed stimulation, degree of ventricular ectopic activity and severity of left ventricular dysfunction.
        Am J Cardiol. 1983; 52: 1190
        • Marchlinski F.E.
        • Waxman H.L.
        • Buxton A.E.
        • et al.
        Sustained ventricular tachyarrhythmias during the early postinfarction period: Electrophysiologic findings and prognosis for survival.
        J Am Coll Cardiol. 1983; 2: 240
        • Mason J.W.
        • Stinson E.B.
        • Winkle R.A.
        • et al.
        Surgery for ventricular tachycardia: Efficacy of left ventricular aneurysm resection compared with operation guided electrical activation mapping.
        Circulation. 1982; 65: 1148
        • Mason J.W.
        • Winkle R.A.
        Accuracy of the ventricular tachycardia-induction study for predicting long-term efficacy and inefficacy of antiarrhythmic drugs.
        N Engl J Med. 1980; 303: 1073
        • Meizlish J.M.
        • Berger H.J.
        • Plankey M.
        • et al.
        Functional left ventricular aneurysm formation after acute anterior transmural myocardial infarction: Incidence, natural history, and prognostic implications.
        N Engl J Med. 1984; 311: 1001
        • Miller J.M.
        • Kienzle M.G.
        • Harken A.H.
        • et al.
        Subendocardial resection for ventricular tachycardia: Predictors of surgical success.
        Circulation. 1984; 70: 624
        • Miller J.M.
        • Marchlinski F.E.
        • Harken A.H.
        • et al.
        Sub-endocardial resection for sustained ventricular tachycardia in the early period after acute myocardial infarction.
        Am J Cardiol. 1985; 55: 980
        • Mirowski M.
        The automatic implantable cardioverter-defibrillator: An overview.
        J Am Coll Cardiol. 1985; 6: 461
        • Mirowski M.
        • Reid P.R.
        • Winkle R.A.
        • et al.
        Mortality of patients with implanted automatic defibrillators.
        Ann Intern Med. 1983; 98: 585
        • Moran J.M.
        • Talano J.V.
        • Euler D.
        • et al.
        Refractory ventricular arrhythmia: The role of intraoperative electrophysiological study.
        Surgery. 1977; 82: 809
        • Mukharji J.
        • Rude R.E.
        • Poole K.
        • et al.
        Risk factors for sudden death after acute myocardial infarction: Two-year follow-up.
        Am J Cardiol. 1984; 54: 31
      1. The Multicenter Postinfarction Research Group: Risk stratification and survival after myocardial infarction.
        N Engl J Med. 1983; 309: 331
        • Norris R.M.
        • Barnaby P.F.
        • Brandt P.W.T.
        • et al.
        Prognosis after recovery from first myocardial infarction: Determinants of reinfarction and sudden death.
        Am J Cardiol. 1984; 53: 408
        • Norris R.M.
        • Sammel N.L.
        Predictors of late hospital death in acute myocardial infarction.
        Prog Cardio-vasc Dis. 1980; 23: 129
        • Pantridge J.F.
        • Webb S.W.
        • Adgey A.A.J.
        Arrhythmias in the first hours of acute myocardial infarction.
        Prog Cardiovasc Dis. 1981; 23: 265
        • Pitt A.
        • Lipp H.
        • Anderson S.T.
        Lignocaine given prophylactically to patients with acute myocardial infarction.
        Lancet. 1971; 1: 612
        • Platia E.V.
        • Griffith L.S.C.
        • Watkins L.
        • et al.
        Treatment of malignant ventricular arrhythmias with endocardial resection and implantation of the automatic cardioverter-defibrillator.
        N Engl J Med. 1986; 314: 213
        • Platia E.V.
        • Reid P.R.
        Comparison of programmed electrical stimulation and ambulatory (Holter) monitoring in the management of ventricular tachycardia and ventricular fibrillation.
        J Am Coll Cardiol. 1984; 4: 493
        • Poser R.F.
        • Podrid P.J.
        • Lombardi F.
        • et al.
        Aggravation of arrhythmia induced with antiarrhythmic drugs during electrophvsiologic testing.
        Am Heart J. 1985; 110: 9
        • Rae A.P.
        • Greenspan A.M.
        • Spielman S.R.
        • et al.
        Antiarrhythmic drug efficacy for ventricular tachyarrhythmias associated with coronary artery disease as assessed by electrophysiologic studies.
        Am J Cardiol. 1985; 55: 1494
        • Rapaport E.
        • Remedios P.
        The high risk patient after recovery from myocardial infarction: Recognition and management.
        J Am Coll Cardiol. 1983; 1: 391
        • Ribner H.S.
        • Isaacs E.S.
        • Frishman W.H.
        Lidocaine prophylaxis against ventricular fibrillation in acute myocardial infarction.
        Prog Cardiovasc Dis. 1979; 21: 287
        • Rinkenberger R.L.
        • Prystowsky E.N.
        • Jackman W.M.
        • et al.
        Drug conversion of nonsustained ventricular tachycardia to sustained ventricular tachycardia during serial electrophysiologic studies: Identification of drugs that exacerbate tachycardia and potential mechanisms.
        Am Heart J. 1982; 103: 177
        • Rosenthal M.E.
        • Oseran D.S.
        • Gang E.
        • et al.
        Sudden cardiac death following acute myocardial infarction.
        Am Heart J. 1985; 109: 865
        • Roy D.
        • Marchand E.
        • Theroux P.
        • et al.
        Programmed ventricular stimulation in survivors of an acute myocardial infarction.
        Circulation. 1985; 72: 487
        • Roy D.
        • Waxman H.L.
        • Kienzle M.G.
        • et al.
        Clinical characteristics and long-term follow-up in 119 survivors of cardiac arrest: Relation to inducibility at electrophysiologic testing.
        Am J Cardiol. 1983; 52: 969
        • Ruskin J.N.
        • McGovern B.
        • Garan H.
        • et al.
        Antiarrhythmic drugs: A possible cause of out-of-hospital cardiac arrest.
        N Engl J Med. 1983; 309: 1302
        • Ryden L.
        • Amman K.
        • Conradson T.B.
        • et al.
        Prophylaxis of ventricular tachyarrhythmias with intravenous and oral tocainide in patients with and recovering from acute myocardial infarction.
        Am Heart J. 1980; 100: 1006
        • Sager P.T.
        • Perlmutter R.A.
        • Rosenfeld L.E.
        • et al.
        Antiarrhythmic drug challenge as an electrophysiologic stress test (abstract).
        Clin Res. 1987; 35: 322A
        • Sager P.T.
        • Perlmutter R.A.
        • Rosenfeld L.E.
        • et al.
        Drug exacerbation of induced ventricular tachycardia (abstract).
        Circulation. 1987; 76: 261-IV
        • Sager P.T.
        • Perlmutter R.A.
        • Rosenfeld L.E.
        • et al.
        Thrombolysis decreases sudden death and arrhythmogenic potential after anterior myocardial infarction with aneurysm formation (abstract).
        Circulation. 1987; 76: 261-IV
        • Sager P.T.
        • Perlmutter R.A.
        • Rosenfeld L.E.
        • et al.
        The time course of sustained ventricular arrhythmias after myocardial infarction (abstract).
        Clin Res. 1987; 53: 322A
        • Sami M.
        • Chaitman B.R.
        • Bourassa M.G.
        • et al.
        Long-term follow-up of aneurysmectomy for recurrent ventricular tachycardia or fibrillation.
        Am Heart J. 1978; 96: 303
        • Santarelli P.
        • Mellocci F.
        • Loperfido F.
        • et al.
        Ventricular arrhythmic induction by programmed ventricular stimulation after acute myocardial infarction.
        Am J Cardiol. 1985; 55: 391
        • Scheinman M.M.
        • Davis J.C.
        Catheter ablation for treatment of tachyarrhythmias: Present role and potential promise.
        Circulation. 1986; 73: 10
        • Schulze R.A.
        • Strauss H.W.
        • Pitt B.
        Sudden death in the year following myocardial infarction: Relation to ventricular premature contractions in the late hospital phase and left ventricular ejection fraction.
        Am J Med. 1977; 62: 192
        • Schuster E.
        • Bulkley B.H.
        Ischemia at a distance after acute myocardial infarction: A cause of early postinfarction angina.
        Circulation. 1982; 62: 509
        • Schuster E.
        • Bulkley B.H.
        Early post-infarction anginaischemia at a distance and ischemia in the infarct zone.
        N Engl J Med. 1981; 305: 1101
        • Skale B.T.
        • Miles W.M.
        • Heger J.J.
        • et al.
        Survivors of cardiac arrest: Prevention of recurrence by drug therapy as predicted by electrophysiologic testing or electrocardiographic monitoring.
        Am J Cardiol. 1986; 57: 313
        • Swerdlow C.D.
        • Bardy G.H.
        • McAnulty J.
        • et al.
        Determinants of induced sustained arrhythmias in survivors of out-of-hospital ventricular fibrillation.
        Circulation. 1987; 76: 1053
        • Swerdlow C.D.
        • Winkle R.A.
        • Mason J.W.
        Determinants of survival in patients with ventricular tachyarrhythmias.
        N Engl J Med. 1983; 308: 1436
        • Theroux P.
        • Waters D.D.
        • Halphen C.
        • et al.
        Prognostic value of exercise testing soon after myocardial infarction.
        N Engl J Med. 1979; 301: 341
        • Tofler G.H.
        • Stone P.H.
        • Muller J.E.
        • et al.
        Prognosis after cardiac arrest due to ventricular tachycardia or ventricular fibrillation associated with acute myocardial infarction (the MILIS study).
        Am J Cardiol. 1987; 60: 755
        • Velebit V.
        • Podrid P.
        • Lown B.
        • et al.
        Aggravation and provocation of ventricular arrhythmias by antiarrhythmic drugs.
        Circulation. 1982; 65: 886
        • Visser C.A.
        • Kan G.
        • Meitzer R.S.
        • et al.
        Incidence, timing and prognostic value of left ventricular aneurysm formation after myocardial infarction: A prospective, serial echocardiographic study of 158 patients.
        Am J Cardiol. 1986; 57: 729
        • Volpi A.
        • Maggioni A.
        • Franzosi M.G.
        • et al.
        In-hospital prognosis of patients with acute myocardial infarction complicated by primary ventricular fibrillation.
        N Engl J Med. 1987; 317: 257
        • Waspe L.E.
        • Seinfeld D.
        • Ferrick A.
        • et al.
        Prediction of sudden death and spontaneous ventricular tachycardia in survivors of complicated myocardial infarction: Value of the response to programmed stimulation using a maximum of three ventricular extrastimuli.
        J Am Coll Cardiol. 1985; 5: 1292
        • Weiner I.
        • Mindich B.
        • Pitchon R.
        Determinants of ventricular tachycardia in patients with ventricular aneurysms: Results of intraoperative epicardial and endocardial mapping.
        Circulation. 1982; 65: 856
        • Wellens H.J.J.
        • Bar F.W.H.
        • Vanagt E.J.D.M.
        • et al.
        Medical treatment of ventricular tachycardia: Consideration in the selection of patients for surgical therapy.
        Am J Cardiol. 1982; 49: 186
        • Wilbur D.J.
        • Garan H.
        • Ruskin J.N.
        Electrophysiologic testing in survivors of cardiac arrest.
        Circulation. 1987; 75: 146-III
        • Wilson C.
        • Adgey A.A.J.
        Survival of patients with late ventricular fibrillation after acute myocardial infarction.
        Lancet. 1976; 2: 124